منابع مشابه
Aptamer-Functionalized Nano-Biosensors
Nanomaterials have become one of the most interesting sensing materials because of their unique size- and shape-dependent optical properties, high surface energy and surface-to-volume ratio, and tunable surface properties. Aptamers are oligonucleotides that can bind their target ligands with high affinity. The use of nanomaterials that are bioconjugated with aptamers for selective and sensitive...
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As knowledge of the structure and function of nucleic acid molecules has increased, sequence-specific DNA detection has gained increased importance. DNA biosensors based on nucleic acid hybridization have been actively developed because of their specificity, speed, portability, and low cost. Recently, there has been considerable interest in using nano-materials for DNA biosensors. Because of th...
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Nanotechnology is currently playing a significant role in the development of biosensors. The sensitivity and performance of biosensors improves drastically by incorporating nanomaterials and adopting new signal transduction technologies. With the rapid development of tools and fabrication processes , nanoscale sensors capable of interacting with extremely small molecules have been developed. Th...
متن کاملBioconjugation techniques for microfluidic biosensors.
We have evaluated five bioconjugation chemistries for immobilizing DNA onto silicon substrates for microfluidic biosensing applications. Conjugation by organosilanes is compared with linkage by carbonyldiimidazole (CDI) activation of silanol groups and utilization of dendrimers. Chemistries were compared in terms of immobilization and hybridization density, stability under microfluidic flow-ind...
متن کاملMicrofabrication Techniques for Chemical/Biosensors
Microfabrication processes for chemical and biochemical sensors are reviewed. Standard processing steps originating from semiconductor technology are detailed, and specific micromachining steps to fabricate three-dimensional mechanical structures are described. Fundamental chemical sensor principles are briefly abstracted and corresponding state-of-the-art examples of microfabricated chemical s...
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ژورنال
عنوان ژورنال: International Journal of Biosensors & Bioelectronics
سال: 2021
ISSN: 2573-2838
DOI: 10.15406/ijbsbe.2021.07.00203